Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | truncNotch |
| GeneSet | BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING |
| Enrichment Score (ES) | 0.73612237 |
| Normalized Enrichment Score (NES) | 1.497126 |
| Nominal p-value | 0.027027028 |
| FDR q-value | 0.35973528 |
| FWER p-Value | 0.999 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GNAS | 630441 1850373 4050152 | 19 | 2.879 | 0.4357 | Yes | ||
| 2 | ADRB2 | 3290373 | 402 | 0.728 | 0.5256 | Yes | ||
| 3 | CCL4 | 50368 430047 | 440 | 0.680 | 0.6267 | Yes | ||
| 4 | MAPK3 | 580161 4780035 | 477 | 0.653 | 0.7239 | Yes | ||
| 5 | HRAS | 1980551 | 1626 | 0.272 | 0.7034 | Yes | ||
| 6 | F2 | 5720280 | 2123 | 0.199 | 0.7069 | Yes | ||
| 7 | ADRBK1 | 1340333 | 2249 | 0.183 | 0.7279 | Yes | ||
| 8 | FGR | 3780047 | 2521 | 0.150 | 0.7361 | Yes | ||
| 9 | MAP2K2 | 4590601 | 3454 | 0.079 | 0.6980 | No | ||
| 10 | AGT | 7000575 | 4988 | 0.034 | 0.6206 | No | ||
| 11 | HTR2C | 380497 | 5287 | 0.029 | 0.6090 | No | ||
| 12 | HCK | 4230592 | 6475 | 0.017 | 0.5477 | No | ||
| 13 | CCL11 | 1770347 | 6960 | 0.013 | 0.5237 | No | ||
| 14 | DNM1 | 1660097 5340519 | 7255 | 0.012 | 0.5097 | No | ||
| 15 | CCR5 | 1980072 5910722 | 8145 | 0.008 | 0.4630 | No | ||
| 16 | GNGT1 | 5220156 | 8845 | 0.005 | 0.4262 | No | ||
| 17 | CCR3 | 50427 | 8997 | 0.005 | 0.4188 | No | ||
| 18 | CHRM1 | 4280619 | 10570 | 0.000 | 0.3343 | No | ||
| 19 | ADRA1B | 2100484 | 11001 | -0.001 | 0.3113 | No | ||
| 20 | ARRB1 | 2650670 2690195 4920592 6660121 | 11269 | -0.002 | 0.2972 | No | ||
| 21 | PTGER1 | 6100132 | 11871 | -0.003 | 0.2654 | No | ||
| 22 | CXCL12 | 580546 4150750 4570068 | 11890 | -0.003 | 0.2649 | No | ||
| 23 | EDN1 | 1770047 | 12016 | -0.004 | 0.2588 | No | ||
| 24 | SRC | 580132 | 12358 | -0.005 | 0.2413 | No | ||
| 25 | FPR1 | 3800577 | 13668 | -0.013 | 0.1728 | No | ||
| 26 | AGTR2 | 2450632 | 14661 | -0.027 | 0.1236 | No | ||
| 27 | RAF1 | 1770600 | 15275 | -0.049 | 0.0980 | No | ||
| 28 | P2RY2 | 2640180 2810128 | 15885 | -0.087 | 0.0783 | No | ||
| 29 | GNB1 | 2120397 | 15968 | -0.093 | 0.0881 | No | ||
| 30 | MAP2K1 | 840739 | 16069 | -0.102 | 0.0982 | No | ||
| 31 | MAPK1 | 3190193 6200253 | 16153 | -0.109 | 0.1103 | No | ||
| 32 | CXCR4 | 4590519 | 16470 | -0.146 | 0.1155 | No |
